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ea0099p14 | Adrenal and Cardiovascular Endocrinology | ECE2024

Improved selectivity of adrenal venous sampling with the use of alternative steroids to cortisol

Alessi Francesco , Costantinescu Georgiana , Peitzsch Mirko , Remde Hanna , Kurzinger Lydia , Schulze Manuel , Lee Myron , Yang Jun , Reinke Martin , Beuschlein Felix , Bornstein Stefan , Lenders Jacques , Pamporaki Christina , Eisenhofer Graeme

Background: Current guidelines recommend adrenal vein sampling (AVS) for the identification of surgically treatable unilateral disease among patients with primary aldosteronism (PA). The cortisol-derived selectivity index (SI) is currently used to assess the success (or selectivity) of adrenal vein catheterization during AVS. However, AVS studies can be non-selective in many cases.Aim: To examine whether the use of SI derived either from 11-deoxycortisol...

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Improved selectivity of adrenal venous sampling with the use of alternative steroids to cortisol

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